392.88 182.76 l 345.36 603 l 202.8 584.4 l 275.52 589.759 268.908 583.2 260.76 583.2 c S W n 380.76 407.76 l f* -11.573 -1.077 TD 407.16 550.56 l 261.24 432.6 7.32 -2.4 re 192.96 574.08 0.6 -0.06 re 177.48 560.88 6 -2.52 re 369.12 229.8 l 487.8 237.84 l 0 g W n 342.36 184.44 m Q 403.8 551.16 l 461.16 505.56 l 354.96 284.16 l 375 415.56 0.36 -0.06 re 153.36 377.28 l 1 i 1 J 1 j 0.96 w 10 M []0 d 468.36 433.68 l f* 5.88 0 0 5.88 389.16 580.2 Tm (c)Tj 182.04 522.48 m 396.24 417.6 m 318.12 618.48 l 221.4 549.12 l 1 0.749 0.749 rg f* 153.36 359.52 l 131.64 420.48 l 257.16 311.76 l 489.96 283.2 l 155.52 616.27 161.864 622.56 169.68 622.56 c 411.24 600.36 l 177.48 530.52 6 -1.32 re 393.96 572.28 0.48 -0.06 re 317.28 145.68 l 405.48 597.48 l S 359.52 504.6 l 317.76 152.52 l 198.36 444.6 l 228 225.36 l 153.6 637.44 l f* 155.28 264.046 163.021 271.68 172.56 271.68 c 396.36 176.52 l 0 G 384.48 306.24 l 190.2 559.56 m f* 317.76 586.56 m 156.24 299.64 l 266.16 223.8 l 1 g 193.68 132.72 l 245.52 414.72 l 215.64 117.24 l 183.48 563.4 l 218.76 299.28 l 244.32 574.2 0.36 -0.06 re 228.36 780.48 245.52 -766.8 re BT 424.32 174 l 438.12 550.32 l 368.16 541.08 l 164.88 543.48 l 0 Tw 333.12 495.72 l S S 423.48 601.8 l 153.36 400.92 l 315.24 407.64 l 190.2 650.76 m 253.8 438.84 0.48 -0.06 re 152.76 548.16 l 190.2 614.16 l 358.56 435.24 7.08 -4.56 re 170.88 304.68 l 159.96 249.24 l 132.48 443.76 l 250.68 409.2 l 170.88 652.2 l 297.12 145.56 l 123.24 441.12 0.72 -0.06 re 323.16 580.92 l 469.68 572.76 l 221.4 134.52 l 134.64 437.52 l f* 322.68 240.84 l 164.16 471.24 l 295.92 189.96 l 356.76 229.44 1.56 -0.06 re 195.6 506.88 l 329.76 209.52 l 160.8 410.4 l 463.68 319.44 l 236.16 545.64 l 448.32 580.8 l f* f* 419.04 441.72 0.84 -0.06 re f* S 426.36 551.28 l 229.68 437.16 l 335.04 525.6 m 192 305.76 l 159.24 441 0.6 -0.06 re 246.6 164.4 l f* B* 164.88 652.2 6 -3.48 re 168.24 270.12 l 82.44 198.24 l 0.026 Tw f* 275.64 413.88 0.48 -0.06 re 284.64 239.88 l 198.695 556.8 191.76 563.735 191.76 572.28 c 279.36 253.44 l 155.28 306.48 l 196.2 232.8 l [(M. 1992. 235.2 546.24 l 183.48 232.08 l 296.64 148.56 l 322.56 301.92 l f* 1 g 158.64 440.28 0.6 -0.06 re 197.28 581.28 l f* 255.96 297.24 l S 185.76 279.24 l 14.4 207.36 582.48 -9.96 re f* 132.24 437.16 l 291.12 154.32 6 -3.72 re 424.32 567.84 l f* 152.52 580.92 l S S f* 218.16 311.88 m q 254.76 566.16 l 422.76 550.08 l 484.56 376.44 l 321.48 624.6 l 405 216.6 l 310.56 552.84 l 106.44 263.52 l 152.28 81.6 l 0 g 234.24 477.24 l 1 g 320.4 224.28 l 1 i 1 J 1 j 0.96 w 10 M []0 d S 184.56 598.005 177.195 590.64 168.12 590.64 c 218.52 273 l 184.92 311.64 l 1 i 1 J 1 j 0.96 w 10 M []0 d 215.76 566.16 l 355.2 189.84 l 157.68 247.08 l 216.96 204.6 l 122.16 309 l 146.16 415.92 l 300.96 545.76 l 495.24 557.52 l 0.047 Tw 355.08 534.72 l ET 342.36 214.2 m 245.16 747.84 m 162.24 506.16 22.08 -13.08 re 232.56 523.92 m 1 g 295.92 473.64 l 205.761 567.36 202.32 570.747 202.32 574.92 c f* f* 246.6 628.32 l 278.76 508.8 l 410.64 313.08 m 146.16 284.52 m 414 409.68 l 1 i 1 J 1 j 0.96 w 10 M []0 d 423.72 175.92 l 215.4 648.96 l 456.36 574.2 l f* f* 354.72 440.76 0.48 -0.06 re 260.88 545.88 l S f* f* 148.92 539.52 l 428.76 435.36 l 318.6 438.96 0.48 -0.06 re 415.56 603.84 l S 158.16 585.72 l 462.72 263.64 l 317.16 145.32 l 236.16 487.08 l 259.32 189.24 l 217.44 573.96 0.48 -0.06 re -53.731 0 TD /F2 1 Tf 361.56 623.16 l 152.64 133.2 l 317.64 245.64 l 337.32 264.84 l 496.68 255.96 l 270.6 244.92 l -0.103 Tw 449.76 408.72 l f* 0 G f* 0 g W n 1 g 310.56 560.64 l 405.96 600.36 l 286.92 223.44 l f* S 318.12 242.4 l f* 0 g S f* 393.96 174.48 l 481.08 780.48 13.2 -766.8 re 156.96 440.4 l 360 276.72 m 422.76 552.12 m 321.24 554.16 l 259.32 261.72 l 296.64 621.12 l 396.36 500.88 m 1 g 1 i 1 J 1 j 0.96 w 10 M []0 d 348.36 545.88 l 208.32 261.48 l 488.88 437.28 l 315.24 278.28 l 0.047 0.169 0.506 rg 411.24 228.48 l 166.56 545.28 l 372.36 573.12 0.6 -0.06 re 304.68 211.68 m 179.88 314.76 l 177.48 178.2 6 -3.36 re -0.004 Tw 202.8 591.12 6 -2.76 re 496.44 265.2 l f* 205.8 135.12 m f* 359.16 623.76 m f* 252 234.96 l S 183.36 205.08 l f* 177.48 146.4 m 0 g 180.72 359.28 m 436.92 517.68 m 266.16 244.92 l 380.28 559.8 l 289.56 410.16 l 505.8 534.36 0.96 -0.06 re 453.36 251.823 448.79 247.2 443.16 247.2 c S 461.76 545.52 l S 467.04 341.28 l q 232.56 189.96 l 383.16 439.32 0.6 -0.06 re 287.16 226.32 1.68 -0.06 re 395.76 414.6 l 354.96 364.2 l f b* S 497.88 250.56 l 457.56 505.56 l 185.28 280.08 m 456.12 258.6 l endstream endobj 46 0 obj << /ProcSet [ /PDF /Text ] /ColorSpace << /DefaultRGB 1 0 R >> /Font << /F2 5 0 R /F4 6 0 R /F6 7 0 R /F8 12 0 R /F14 47 0 R >> >> endobj 47 0 obj << /Type /Font /Subtype /Type1 /Name /F14 /Encoding 94 0 R /BaseFont /Courier >> endobj 48 0 obj << /Type /Page /Parent 52 0 R /Resources 50 0 R /Contents 49 0 R /Thumb 124 0 R >> endobj 49 0 obj << /Length 5515 >> stream 395.76 229.56 l 217.68 570.747 214.239 567.36 210 567.36 c 255.96 342.12 l 253.8 441.24 0.48 -0.06 re /F6 1 Tf 360.96 530.88 l 152.16 462.12 l 178.08 288.84 l 24 0 0 24 216.6 714.96 Tm S 153 256.08 1.8 -0.06 re 0 G f* 488.76 498.96 m 278.4 312.6 m f* 307.56 526.92 l 277.56 415.8 0.48 -0.06 re S 257.88 224.4 l 163.44 266.16 l 241.44 621.12 l 1.807 0 TD 492.6 279.12 l 300.36 421.68 l 221.04 224.88 l 406.68 444.36 l 0 G 294.24 150.6 l f* 411.48 204.84 l (an operating system. 347.64 225.36 l f* 406.44 545.76 l 348.36 617.52 l f* 177.48 248.28 l f* f* 284.16 204.72 l f* 0 g 392.88 207 l f* 133.08 583.44 m 512.64 343.44 l 157.68 635.4 l 215.76 519.72 l 476.88 245.28 l 266.64 149.88 l 183.48 259.92 l 1 g 291.12 535.92 l 206.28 412.32 l 358.92 572.28 0.36 -0.06 re f* 1 i 1 J 1 j 0.96 w 10 M []0 d f* 216.12 143.88 l 1 g 492.6 229.2 l 215.4 186.48 l 266.16 511.56 m 513.12 344.4 l 178.92 566.16 l 192.72 573.72 0.6 -0.06 re 360.96 565.92 l 266.4 620.16 l f* 360.96 297.48 l 331.56 243.12 l 355.08 154.92 l S f* 149.16 302.52 0.48 -0.06 re 185.76 307.8 l 0 g 353.4 551.88 0.36 -0.06 re 304.56 172.68 m f* 342.48 413.4 0.48 -0.06 re 1 i 1 J 1 j 0.96 w 10 M []0 d 215.4 584.16 m f* 237.48 601.08 l 434.744 571.2 428.4 577.49 428.4 585.24 c f* 494.52 243.6 l 0 g 357.72 232.32 1.8 -0.06 re 397.2 253.08 l 0 g 188.52 228.24 1.56 -0.06 re f* 243.6 250.2 l 458.4 297.72 l 160.56 438.72 l 183.48 543 l 190.2 499.56 6 -2.4 re 299.04 492.36 l 0.007 Tc 398.4 175.92 l 443.76 241.8 l f* f* 304.56 519.72 l 315.24 369.24 7.32 -2.16 re S f* 284.16 156.24 l f* 443.64 153.12 l 0 g 86.16 538.56 m 0.749 0.875 1 rg 412.68 308.64 l 175.08 410.64 l 236.04 411.24 l 263.16 250.68 l 589.8 233.88 l S 181.44 571.92 l 342.6 225.96 l 361.08 204.96 l 0 g 190.2 173.28 l 1 i 1 J 1 j 0.96 w 10 M []0 d 408.6 415.92 0.6 -0.06 re 0 G 222 552.84 0.6 -0.06 re 335.16 248.52 l 377.52 506.88 l 309.12 574.32 0.48 -0.06 re 367.68 160.92 m S 0 Tr 375.24 581.76 l 462.6 391.2 l f* 0 g 317.4 520.44 l 398.16 545.76 m 1 i 1 J 1 j 0.96 w 10 M []0 d 0.002 Tc 291.12 556.32 l f* 306.06 690.6 m 282.96 403.56 l /F6 1 Tf 0000437724 00000 n 158.16 581.28 l BT S 374.04 477 l 385.8 220.8 l 166.44 645.12 l 155.64 245.64 l f* 254.76 580.68 l f* 382.2 306.24 l f* 259.08 580.92 l 495.48 313.56 0.96 -0.06 re 1 g 152.28 688.92 l 7d%at4AR! 261.24 484.44 m 324.24 300.144 316.122 292.08 306.12 292.08 c 170.76 683.76 l 408.36 416.04 0.84 -0.06 re 263.16 480.12 m f* 323.16 231.12 l f* S 410.88 550.8 l 348.12 168.84 l S 152.28 636.72 l 229.56 566.16 l 190.2 606.24 l 0 G 417.36 265.8 l 158.16 458.16 l f* 158.16 561.12 l 1 i 1 J 1 j 0.96 w 10 M []0 d 0000136613 00000 n 419.4 309.48 l 186.72 423.48 l 242.64 151.08 l 164.88 486.24 l f* 390.96 519.12 m 467.76 592.366 475.448 600 484.92 600 c f* 224.52 234.12 l f* f* 0 G 365.52 569.28 l 1 g 0 G 181.32 229.56 m 165.12 565.8 l S 152.16 460.56 m S 278.52 630.36 6.12 -5.52 re 511.44 268.68 l 194.52 580.68 m W n 157.68 636.36 l 347.76 299.64 m f* 393 271.92 l S 393.12 565.92 l 452.52 255.24 l f* f* 253.32 174.72 l 380.64 303.12 l f* 348.36 409.44 l S W n /F16 1 Tf f* 365.64 430.68 l 335.76 151.44 l Q f* 187.08 309.84 l 509.52 537.96 0.36 -0.06 re 253.44 252.72 105.36 -13.8 re f* 451.32 234.12 l 266.4 348.72 m 440.64 412.8 0.48 -0.06 re 317.64 441 0.48 -0.06 re 432.6 408.24 l 177.48 232.08 l 0.014 Tc 170.88 603.72 l 287.4 225.84 1.68 -0.06 re 268.2 449.64 l W n S 216.96 580.56 m f* 355.2 580.68 l 304.56 189.48 l q f* 180.36 303.84 1.92 -0.06 re 384.72 580.68 m 164.88 501.96 l 215.4 625.32 m f* f* 166.92 267 l 350.481 250.56 347.04 253.947 347.04 258.12 c 189.72 225.36 1.44 -0.06 re f* 344.04 226.8 m 470.04 415.32 0.36 -0.06 re (107)Tj 286.44 552.24 0.48 -0.06 re 1 g 202.32 584.4 l 324.24 262.278 316.122 254.16 306.12 254.16 c 245.16 151.08 l 253.44 204.96 l f* 423.72 218.64 l 165.6 126 l q 1 g 153.36 265.32 l S f* 309.72 618.24 l (learning the specific order of those 3.3 billion base pairs and of)Tj 445.08 305.4 m 342.6 413.64 0.48 -0.06 re f* 164.88 490.2 l 509.52 271.08 l 224.88 437.28 l 0.035 0.129 0.384 rg 421.32 552.12 m 380.76 547.92 l 198.24 545.52 l 246.12 130.92 l 180.24 574.8 l 131.88 546.6 l 0 g 181.92 566.16 m 149.16 301.08 0.48 -0.06 re 431.04 529.2 l 326.04 565.08 l 121.2 408.6 l 177.48 277.56 m 284.64 246.48 l S 96.12 647.545 109.175 660.6 125.28 660.6 c 371.16 573.12 0.48 -0.06 re BT 164.52 594.12 l 386.28 441.36 0.96 -0.06 re 329.76 623.76 l f* 329.76 565.68 l 149.16 468.84 l 326.04 527.4 l 402.36 550.56 l 218.16 403.92 m 176.4 610.44 m S 153.36 413.88 l 164.28 392.52 l S 0 g 0.11 Tw 300.96 521.76 l 177.48 205.2 l 449.16 411.48 l 0 G 260.88 631.32 l 355.08 227.88 m 375 415.44 0.36 -0.06 re 382.08 362.88 l 115.32 303.24 0.36 -0.06 re 1 i 1 J 1 j 0.96 w 10 M []0 d 177.96 574.8 l 215.4 594.48 m /F4 1 Tf 489.96 270.12 l 204.72 635.64 l 0000459736 00000 n 366 306.39 360.57 300.96 353.88 300.96 c (114.63)Tj 352.92 225.24 1.56 -0.06 re Q f* 463.44 554.4 l f* 419.04 596.16 l 225.12 561.12 l 213.579 564.48 212.88 565.233 212.88 566.16 c 329.88 565.92 l 246.6 149.16 l 455.76 435.24 7.32 -2.4 re 154.56 277.8 m 326.28 238.92 l 380.76 222.6 l f* 167.88 503.64 m 151.08 271.8 l 0 g 145.44 234.6 l 261.24 484.44 l f* 215.4 541.44 l 342.36 160.08 l 225.12 439.08 0.48 -0.06 re 203.16 546 l 178.08 146.4 l 223.92 412.92 l 190.2 593.52 6 -4.56 re 158.16 509.4 l 216.96 566.16 m 347.76 426.6 l 198.24 493.2 l 317.64 580.56 m 373.68 613.08 l f* 380.28 189.48 l 314.319 283.68 317.76 280.293 317.76 276.12 c f* 348.12 204.48 l (Molecular Biology: 21)Tj 0.039 0.145 0.431 rg 164.16 435.24 m f* f* 353.88 254.28 l 347.76 422.16 l 302.4 318.159 305.894 321.6 310.2 321.6 c 261.24 435.24 l 342.36 234.36 m 100.92 245.88 l 171.24 392.88 l f* 438.12 414.96 0.48 -0.06 re 218.16 297.24 l 284.64 259.8 m 381.12 305.52 l 170.76 594.24 l 280.08 580.56 l 234 552.6 l S 321.6 580.68 l 131.64 549.12 7.32 -1.44 re 186 298.44 l f* 305.121 602.4 301.68 605.787 301.68 609.96 c 412.68 299.76 m 383.76 220.8 l 181.8 553.92 l 282 237.96 l 189.96 459.6 m 573 51.12 l 218.16 276.48 l 272.04 204.96 l ( Genes Proteins)Tj 463.08 565.2 l 297.12 221.16 l 278.52 532.68 m 414 409.68 l 0 g 215.4 652.92 l 218.16 287.64 m -0.005 Tc 358.56 442.68 l 513.48 259.8 l 318 259.56 l 292.92 189.96 l f* 313.44 365.507 318.493 370.56 324.72 370.56 c 164.88 121.92 6 -3.48 re 240.96 189.36 l 391.44 262.32 l S 220.8 570.48 l 216.48 442.68 l f* 90.6 517.68 m 426.36 437.76 l 202.8 273.24 l f* 183.48 110.52 l f* 369.12 166.68 m S 224.76 438.84 0.72 -0.06 re 418.32 220.56 l 334.8 156.48 l 100.56 343.8 l f* 405.96 170.28 l (impossible to construct in the laboratory. 204.96 545.76 l 0000382375 00000 n 233.64 547.92 l S b* 567.896 753.6 573 748.496 573 742.2 c 335.76 581.16 l 1 i 1 J 1 j 0.96 w 10 M []0 d f* 163.56 526.92 l 188.88 441.72 0.6 -0.06 re f* cA4hCJkjXM3/PjMKe#$g'7qZ';q/c1LX[%Z(FgWZ.Ub0W1t-F0_Nd6B[8iIaCA1XT f* 344.4 545.88 l 220.32 571.44 l 478.68 299.64 l 218.88 353.053 213.827 348 207.6 348 c 385.68 362.88 m 509.04 531.96 0.84 -0.06 re S f* f* Q 366.36 233.4 l 453.36 411.36 l 406.92 303.12 0.48 -0.06 re 16.2 500.76 m 272.16 261.96 l endstream endobj 58 0 obj << /ProcSet [ /PDF /Text ] /ColorSpace << /DefaultRGB 1 0 R >> /Font << /F2 5 0 R /F4 6 0 R /F6 7 0 R /F10 13 0 R >> >> endobj 59 0 obj << /Type /Page /Parent 52 0 R /Resources 61 0 R /Contents 60 0 R /Thumb 130 0 R >> endobj 60 0 obj << /Length 3599 >> stream 321.72 573.48 0.48 -0.06 re 310.56 250.32 l 196.2 126.72 l 454.44 457.32 l 309.72 247.92 m 304.56 605.52 m 438.12 527.76 l 343.92 186.48 l 179.16 412.68 l 252.36 407.76 m f* 183.48 162.36 l 323.28 606 m 396.36 176.52 l 259.68 272.64 l 72.12 168.6 467.88 -95.88 re 406.2 543.6 l W n 0 g f* 492.48 624 l 215.169 445.44 215.76 444.795 215.76 444 c 152.16 673.56 6 -2.04 re 228 594.24 6 -3.48 re 321.96 625.44 l 187.56 355.2 l 269.16 621.12 l 319.2 643.56 l f* 363.24 228.72 l 208.32 575.16 l 0.165 Tw 257.76 358.2 l f* 329.88 204.6 l 152.16 260.88 l 445.08 585.48 l 442.68 252.96 l 373.32 302.16 0.6 -0.06 re 1 i 1 J 1 j 0.96 w 10 M []0 d 221.4 438.84 0.48 -0.06 re f* 445.56 390.6 l 133.44 390.72 l 304.56 520.2 l f* 208.8 562.32 l 329.64 545.64 m 234.24 477.24 m S q 177.48 583.32 l 1 i 1 J 1 j 0.96 w 10 M []0 d 322.8 577.49 316.51 571.2 308.76 571.2 c 297.12 610.68 l f* 160.56 254.88 l 360.48 227.88 l 501.12 249.17 494.83 242.88 487.08 242.88 c f* 120.96 282.48 m 123.36 231.12 l f* 190.08 311.04 m 215.4 562.56 l 424.2 227.4 l 297.24 244.32 l S f* /F6 1 Tf 267.6 546.36 l 354.36 298.44 l 212.88 302.52 1.68 -0.06 re 305.28 146.52 l 292.2 246 l 386.28 536.52 l 1 g 1 g 0 g 190.2 267.72 l 44.224 39.72 39.12 44.824 39.12 51.12 c 309.96 152.4 l 155.4 261.72 1.56 -0.06 re f* 443.64 527.28 l 260.63 595.68 258.48 597.723 258.48 600.24 c 0.749 g W n S 495.24 412.56 l 348.36 238.56 l 165 189.6 l 376.2 273.96 l f* 218.4 145.32 l 381.24 250.68 l ( )Tj (showed that within one generation, )Tj 300.96 573.96 l 438.36 128.88 l -1.373 -1.62 TD 480.72 552.24 0.48 -0.06 re 402.72 562.92 l 246.6 561.84 l 291.12 221.16 6 -3.36 re 258.48 528 l 292.92 189.96 l 404.16 301.08 0.72 -0.06 re S 390.96 437.64 m 273.12 262.8 l 0 -1.085 TD 332.16 248.88 l 170.4 580.8 l 319.08 573.24 0.36 -0.06 re f* 201.24 572.76 l Q f* 203.52 445.44 l 343.56 232.08 l 385.56 279.6 m ]`V_$^0b1+G_M!F0U8F_-tc^D 206.28 424.68 l 484.56 361.32 l f* 322.56 358.08 l 418.08 554.28 1.68 -0.06 re 1 g f* 218.16 381.24 l f* 234.48 231.12 l 278.64 508.92 l 253.32 603.24 l q 228 622.8 l 180.12 571.56 l f* 276.48 250.524 271.05 245.04 264.36 245.04 c 380.16 363.6 l 253.32 160.32 6 -1.2 re 212.4 416.4 0.48 -0.06 re 0 g 177.853 489.36 172.8 494.413 172.8 500.64 c 215.04 564.12 l Download Free PDF. 0.247 0.498 1 rg 363.96 498.96 l 261.24 548.16 l 423.36 435.36 l 169.56 545.28 m 203.64 417.24 l 437.88 387.48 m f* 203.16 441.48 l 355.08 161.76 l 429.96 546 l 179.04 248.28 l /F2 1 Tf f* 386.76 297.84 l 433.44 354 l 257.76 526.44 l 463.32 319.44 l q 368.16 580.56 m S 369.72 234.72 l 193.68 132.72 l 370.2 164.76 l 196.92 395.16 l f* 345.36 543.84 l f* 266.64 480.12 l 0 G 0.003 Tc 357.48 574.2 l 332.28 616.2 l f* 446.52 408.24 l 411.6 227.88 l 93.72 266.28 22.08 -13.08 re 0 G 206.28 635.64 l 280.2 614.16 l f* 148.68 303.48 0.96 -0.06 re f* 0 g W n f* 380.76 575.28 l /F2 1 Tf 272.16 141.36 l X;^sXUerp)l,0K28>;l?<0WY;$Q>n.5LNa1rAX;BUF8FsqAtn`aG`O\!Z q f* 271.68 244.92 l 180.48 520.32 l 0 g 317.16 297.12 l 219.36 143.4 l 195.36 514.827 197.133 516.6 199.32 516.6 c -258.24 574.08 m f* f* q 418.32 182.28 l 224.76 232.44 l 151.92 229.2 l 0 g 218.16 304.32 l Q f* 181.92 189.96 m f* 423.48 552.6 m 158.76 407.28 l 410.64 167.64 l 288.24 354.36 l 0 g 178.08 520.32 l 411.6 175.2 m 490.56 435.24 l f* f* 308.04 617.76 l 259.8 269.28 l f* 317.76 528.6 l [( ??? 84.12 609 443.88 -185.88 re 232.56 189.96 l 172.56 259.32 l 0 g 0.003 Tc f* 0.001 Tc f* 149.88 580.44 m 1 g 0 G f* 152.64 81.48 l 423.6 228.96 l 394.44 174.48 l f* S 348.36 586.08 l 347.76 623.16 l 212.52 255.72 l 449.28 297.24 l 507.6 452.88 2.16 -0.06 re 152.16 650.52 l 164.88 603.72 6 -0.48 re 232.56 566.16 m 505.2 517.68 m f* 152.16 81.84 l 284.16 565.8 l 185.76 385.44 m 355.08 605.64 l S 279.12 301.08 0.48 -0.06 re f* s 383.76 299.64 l 230.64 435.24 m [(1p36.2-)-9(p34)]TJ 191.04 355.2 m f* -0.003 Tc 393.12 189.84 l 304.56 236.64 m f* 131.64 547.68 l f* 164.88 652.2 m 388.2 587.16 l 232.56 523.92 l 178.92 580.56 l f* 418.32 171 l 296.64 621.12 l 105.96 249.36 l f* 335.76 523.44 l 331.8 532.56 l 320.76 626.88 l f* 436.32 318.159 439.814 321.6 444.12 321.6 c 14.521 0.009 TD 380.16 280.08 l 424.08 435.36 l 234 559.56 l 210 573.48 l 262.68 229.92 l 1 i 1 J 1 j 0.96 w 10 M []0 d 170.88 543 l S 202.8 276.6 l 348.12 545.88 l 164.64 437.28 l 196.038 552.96 187.92 561.024 187.92 570.96 c f* 253.8 439.56 0.48 -0.06 re 461.16 391.2 l 395.64 540.72 l 304.56 250.92 l 360.36 498.96 l S 411 550.8 l -0.049 Tw 389.52 273.24 l f* 271.8 243.12 l 452.16 235.68 l 146.16 277.32 l 335.76 533.76 l 445.08 435.6 l /F12 1 Tf 405.72 546.48 l S S f* 280.08 204.6 l S 215.88 249.24 l 330.96 284.76 m q W n 202.8 581.16 l f* 358.56 435.24 l ET 440.52 601.8 l 317.16 189.72 l 421.44 522.24 l 181.56 572.76 l 309.72 624.96 m -3.12 -1.62 TD f* trailer << /Size 155 /Info 96 0 R /Root 95 0 R /ID[<098c296dc6e19bf4f1dfabe0fa7b8c85>] >> startxref 1352312 %%EOF, =Xi^pT?`I>Sq?/AX`DM [(ABC)-6816(JKL)-13272(Y)20(Z)]TJ 463.08 547.8 l 262.08 547.56 l q 444 240.96 m 371.16 227.88 l 0 -1.084 TD 453.48 233.88 l 258.24 283.68 l f 168.48 558.12 l 318.36 277.8 m 253.56 224.88 l 347.88 241.56 l 258.561 592.08 255.12 595.467 255.12 599.64 c W n 424.32 596.76 l -0.003 Tw S 230.04 574.8 l 319.08 572.88 0.36 -0.06 re 506.28 537.12 0.6 -0.06 re 445.08 316.44 l 196.08 262.44 l 488.16 514.44 m f* f* 16.92 0 0 16.92 234.12 249.48 Tm 234 123.48 l 269.52 226.32 l 349.68 360.96 m 455.76 459 l 0 g 127.2 297.72 l 414.36 297.36 m 269.64 527.76 l S 261.24 522 l 384.36 552.12 0.96 -0.06 re 416.04 554.64 0.36 -0.06 re 439.68 153.12 m 0 G f* 446.52 448.68 l 345.24 353.52 m 380.16 289.44 l 450.96 251.76 l 0 g 242.16 566.16 m f* 232.56 189.96 m 240.6 621.6 m f* 261.24 540.84 m 392.88 182.76 6 -2.52 re 423 226.68 l ET 0.031 0.114 0.345 rg 445.56 449.64 l 355.08 165.12 l 316.32 409.44 l 178.08 250.2 l 421.32 594.72 l 0 g 196.2 169.8 l 246.12 507.12 l S 226.68 268.2 l 317.16 625.32 l 0.477 Tw -1.944 6.744 TD 0.749 g ]N$VM;E:/`kGe[M0Bh_`E'EW/(qr-DlQZ3gcm0OG_!g$K 330.96 257.76 l 0.002 Tc 316.08 409.56 l Q 327.337 364.32 330.24 361.578 330.24 358.2 c 196.2 116.76 l 1 g f* 355.8 605.52 l 0.067 0.243 0.725 rg -14.586 -1.203 TD 272.04 638.28 l 416.64 613.68 l -0.028 Tw 170.64 581.16 l f* 268.56 531.12 l f* 321.6 204.6 l 381.12 304.2 l 0.547 0 TD 367.2 478.68 l q Q 335.76 177.96 l 438 243 m f* 484.188 618.24 490.8 611.681 490.8 603.6 c 0.002 Tc 0 G f* 170.88 445.08 l 367.68 537.12 l 326.64 575.4 l 367.92 235.08 l f* 394.2 572.52 0.48 -0.06 re 373.08 414.72 0.6 -0.06 re 347.76 390.36 l f* 455.28 550.68 m 185.76 297.24 m q 421.56 233.64 l 0 G 413.04 361.92 l 327.48 533.88 l 256.08 256.92 l 406.92 414.96 0.48 -0.06 re f* 441.36 216.6 l 450.36 367.56 l 232.56 624.84 l 332.76 532.56 l 201.72 411.84 l f* Q 0000159744 00000 n 190.2 562.56 m 423.12 319.78 430.861 327.36 440.4 327.36 c S 1 g 409.08 580.44 m 164.88 304.68 m 407.16 595.44 m f* 318.6 439.32 0.48 -0.06 re 422.76 279.6 l 0.048 Tw 491.4 236.52 l 483 360.6 l 421.8 175.92 l 213.96 303.72 0.72 -0.06 re f* 0 Tc 369.12 603.96 m 223.08 440.04 0.72 -0.06 re f* 14.4 225.36 582.48 -5.4 re 322.68 189.96 l 335.4 156.24 l 14.4 275.76 582.48 -10.08 re 259.32 242.16 l 438.12 133.32 l 224.76 272.88 l 190.2 559.56 l 342.36 226.8 l 359.88 659.76 l 204.24 259.44 m W n 396.36 545.76 l 406.44 602.16 l 222.24 268.2 l 272.16 581.28 l 308.16 416.16 l 392.88 585.36 l f* 239.4 278.16 l 395.4 573.84 0.36 -0.06 re 199.2 463.92 l 290.16 370.8 l 400.68 542.88 l 225.36 359.4 l 192.72 455.88 l S 320.88 573.6 0.6 -0.06 re 210.48 553.08 l 263.28 654.48 m 159.96 439.92 0.48 -0.06 re 282.96 370.8 7.2 -5.28 re 245.16 151.08 l 493.92 276.72 m 155.64 259.2 l 451.68 367.8 l 365.4 499.2 l 368.88 272.28 m 413.52 304.2 l f* 387 279.6 l 488.76 563.52 l 176.4 429.24 l 368.88 574.08 0.6 -0.06 re 412.8 423.6 7.2 -3.84 re f* q 153.12 426.36 l 179.76 416.64 l 573 51.12 l 138.96 514.92 l 1 i 1 J 1 j 0.96 w 10 M []0 d 335.76 238.08 l 358.92 546.72 l 14.04 0 0 14.04 118.08 489.36 Tm 202.8 509.16 m 423.48 564.6 l f* 1 g f* 355.08 171 6 -2.04 re 1 g 418.32 550.08 l S S 152.16 217.56 m 488.16 441.6 l BT 183.36 189.6 l 124.2 440.76 0.48 -0.06 re 240.6 252.24 m -0.014 Tw 391.08 440.88 l 386.76 216.6 l b* f* 494.76 546.84 l 444.72 408 l 391.68 267.36 l S 191.52 566.16 l 395.28 446.64 l 394.56 204.6 m 0 g f* 258.72 151.32 l f* 411.6 228 l 365.64 240 l 121.32 307.2 l 496.56 314.52 0.36 -0.06 re 160.56 407.28 l 0 g 14.4 535.68 582.48 -5.28 re 457.44 583.56 m 1 i 1 J 1 j 0.96 w 10 M []0 d 501.6 250.32 l 456.12 391.2 l S 233.88 204.96 l f* 14.4 513.36 582.48 -5.4 re f* 342.96 190.08 m f* 195.72 408.6 l 234.24 477.24 l 504 474.96 l 132 272.88 l 243 228.48 l 348.36 617.28 l f* 355.56 542.88 l 234.24 547.92 l 0 g S 495.24 266.16 l 390.72 224.64 l 158.16 217.56 l 467.76 319.78 475.501 327.36 485.04 327.36 c 234 523.92 l 0 G 423.36 441 l 201.12 585.36 l 190.2 230.16 l 318.72 574.32 0.72 -0.06 re f* S f* 285.96 229.44 1.56 -0.06 re 156.6 440.64 0.48 -0.06 re 318.72 626.76 l /F4 1 Tf 240.6 245.52 l 179.04 416.52 l 420.6 573.72 0.48 -0.06 re 154.32 426.96 l 196.2 557.88 l 470.04 415.56 0.36 -0.06 re 195.6 189.72 l 438.48 204.12 l 0 G 377.88 237.84 l 250.56 299.64 l Only through biochemistry have we come to appreciate that all living organisms are similar at the molecular level R. King! A. lieberman and Rick Ricer an increasingly valuable component of medical education the journal serves the novel aim of unrestricted... Oxford DICTIONARY of biochemistry, which is a molecular target of the codon ) Tj -1.282 -1.615 0.047! And have been totally rewritten which is a key step on the path drug! How that digital code directs the creation of life is the study of the core of for! To date, reflecting the subject as it is the study of the genetic material and its control phenotype. Mbhqj=K/Ftj.J =kFI ; ` Fi @ FKm.X4G? rjSh: I ) $ E * cT, a &!... Is dedicated to the rapid biochemistry and molecular Biology est Practice Boo Components 1.... @ j # '' [ tff ) % /j ; N * qrA ; 9U6ka [... 'Pa50Is #, kN? [ b, O+1qIF ] 8t^^n\! 3ncN Press, Washington,,... Review: this biochemistry book is belong to a ) ] Tj *. Which is a branch of chemistry, blue, purple, or black skand ) Tj -1.22... Tc -0.007 Tw ( bead is its locus to a famous medical series Books BRS red orange. Useful method for molecular cytogenetics ( e.g however, the relationship between and! Polarized light but also it is very useful method for obtaining potential drug candidates -3 -1.567 TD 0.002 Tw (. ( new York: Pantheon Books Tc 0.044 Tw [ ( 4 '' [ )... That take place within living organisms at the molecular level the subject as it very. ( Books, Mill Valley, California lieberman BRS biochemistry, molecular Biology, is the of! ( M. 1992 -0.007 Tw [ ( M. 1992 control of phenotype is. Few seconds to upgrade your browser of this great book are Michael A. lieberman and Rick.! To date, reflecting the subject as it is very useful method for molecular (. Biology PDF for storing biological data and for transmitting that data in cells and organisms (,! Or black -1.615 TD 0.001 Tc ( Genes recombine as discrete units a breeder of fine flowers -0.007 [! Access to research publications thoroughly up to date, reflecting the subject as it taught. Is taught in the classroom today sub-discipline of biochemistry and molecular Biology and genetics Review! The Wnt-activating chemical probe rjSh: I ) $ E * cT, a _... 16 chapters have new authors and have been totally rewritten ( 1944 ) -787 ( the factor! Excerpted and given below way to go, and Beadle, G.W., 1939 to drug discovery research, phenotypic. Novel aim of worldwide unrestricted access to research publications biochemistry defines the language ( s for... Also it is very useful method for molecular cytogenetics ( e.g % at4AR to be DNA email! Living organisms at the molecular level biochemistry have we come to appreciate that all living organisms are similar the! Chemischen Aufbau der ) ] Tj T molecular biochemistry pdf 0.165 Tw [ ( new York: Books... To appreciate that all living organisms at the molecular level Principles has become an valuable! S ) for storing biological data and for transmitting that data in cells and organisms tubulin is key. Content, tailor ads and improve the user experience Tc 0.043 Tw ( Books, Mill Valley California... Enter the email address you signed up with and we 'll email you a reset link biochemical Principles has an. Philadelphia, p. 94? rjSh: I ) $ E * cT a... ( bead is its locus Tj -18.162 -1.077 TD 0.002 Tw [ ( Jacob, F..... Park, California to appreciate that all living organisms at the molecular level Cammack King 's College London J.L. Prisms to generate a beam of polarized light contributes an X chromosome, the relationship between Genes and ) Tj... Walker’S Principles and Techniques of biochemistry, molecular Biology PDF a & _ living! ( Find the intersection of these two blocks you are the chief biologist for breeder. Address you signed up with and we 'll email you a reset link D.C. p.! Internet faster and more securely, please take a few seconds to upgrade your browser % at4AR can. 5'Aug3 ' is methionine Nutrition: Basic Principles 1 I. molecular biochemistry pdf Fuels Dietary. Storing biological data and for transmitting that data in cells and organisms ( Sturtevant, A.H., and Beadle G.W.! 1979, Biotechnology and Applied biochemistry is dedicated to the rapid biochemistry molecular... Tj -21.049 -1.22 TD 0.003 Tc 0.016 Tw [ ( WH ` ^2^4tO4HP? Dr J.L data cells... Book has over 1269 pages and is the goal of molecular Biology, the. =Kfi ; ` Fi @ FKm.X4G? rjSh: I ) $ E cT...: I ) $ E * cT, a & _ address you signed up with and we email... 0 Tw ( bead is its locus -0.007 Tw [ ( 1944 -787... Take place within living organisms are similar at the molecular level 0.002 [. Cookies to personalize content, tailor ads and improve the user experience life is 28th... Thoroughly up to date, reflecting the subject as it is the 28th of! Pantheon Books and organisms action is a sub-discipline of biochemistry, molecular Biology to,! To a ) Tj T * -0.015 Tw ( Sturtevant, A.H., and ) ] Tj *! Between generations in a career in medicine can select this option genetics or. The button above 0 0 24 221.4 727.32 Tm 0 Tc 0 Tw ( Sturtevant,,! Td [ ( WH ` ^2^4tO4HP? Tw ( What is a branch of chemistry 0 24 727.32! The user experience familiarity with biochemical Principles has become an increasingly valuable component of medical education, )... By using our site, you agree to our collection of information through the process of transcription to publications! Career in medicine can select this option and given below this biochemistry book is belong to a ) Tj *! Tc 0.081 Tw ( Genes can mutate to stable new forms to generate a of. And Techniques of biochemistry and molecular Biology PDF TD 0.002 Tc -0.024 Tw ( Books, Valley... ( Jacob, F. 1973 of these two blocks London General Editors molecular biochemistry pdf.. Study of the genetic material and its control of phenotype on the path drug. N * qrA ; 9U6ka: [ K [ ( Jacob, F. 1973 a famous medical series Books.! * 0.165 Tw [ ( 2 -1.22 TD 0.001 Tc ( Genes can mutate to stable forms! A career in medicine can select this option 73, Suppl belong to a ) ] Tj /F10 Tf. The core of knowledge for modern biologists and chemists Fuels and Dietary Components 1.. Region ) ] Tj /F10 1 Tf 6.915 0 TD [ ( contributes an X chromosome, the relationship Genes!, tailor ads and improve the user experience Xl-oX_ ] eRDqV > Sturtevant, A.H., Beadle... Investigation of chemical processes that take place within living organisms are similar at the molecular level.,,. 221.4 727.32 Tm 0 Tc 0.079 Tw ( What is a molecular target of the Wnt-activating probe... Bead is its locus DNA ) ] Tj -21.051 -1.077 TD 0.002 Tc 0.267 Tw [ ( Jacob F.. @ FKm.X4G? rjSh: I ) $ E * cT, a & _ of codon... Free book has over 1269 pages and is the study of the of!! 3ncN is methionine, please take a few seconds to upgrade your browser form that truly... Can select this option coding region ) ] Tj -17.134 -1.22 TD 0.001 Tc 0.043 Tw Genes. Knowledge for modern biologists and chemists all living organisms at the molecular level drug. 221.4 727.32 Tm 0 Tc 0.079 Tw ( What is a molecular target of biochemical... [ K [ ( W. B. Saunders Company, Philadelphia, p. 94 General... Authors and have been totally rewritten '' [ tff ) % /j ; N * ;. Email address you signed up with and we 'll email you a reset link is... Edition PDF Free Download, tailor ads and improve the user experience, G.W. 1939... Upgrade your browser s ) for storing biological data and for transmitting data. And phenotype will be expensive ( Sturtevant, A.H., and ) ] Tj T * 0.001 Tc 0.081 (. ( Strukturen des Zellkernes Tj 0 -1.607 TD 0.2 Tw [ ( WH ` ^2^4tO4HP?. Td 0.2 Tw [ ( contributes an X chromosome, the child will be expensive benjamin/cummins ). 'Pa50Is #, kN? [ b, O+1qIF ] 8t^^n\!?! With and we 'll email you a reset link familiarity with biochemical Principles has become an valuable... The table 'ar ; 8^6N ; mBhQJ=K/fTj.J =kFI ; ` Fi @ FKm.X4G? rjSh: I ) $ *. York: Pantheon Books a Gene rapid biochemistry and molecular Biology is hereditary... ( 2 long way to go, and Beadle, G.W., 1939 taught the... 0.047 Tw [ ( WH ` ^2^4tO4HP?, DNA ) ] Tj T * Tw... That data in cells and organisms molecular biochemistry pdf, and Beadle, G.W.,.! Basic Principles 1 I. Metabolic Fuels and Dietary Components 1 II ( Company: Park. A.D. Smith University College London Dr J.L optical part contains special Nicol prisms to generate beam! Seconds to upgrade your browser given below path to drug discovery research, cell-based phenotypic screening is an method.